Precision Immunology for

Precision
Immunology for

Immune-Driven Diseases

Immune-Driven Diseases

Restoring Balance in

Human Biology

Ashta Therapeutics is an emerging biotech restoring balance in human biology through precision immunology - pioneering a first-in-class GPCR mechanism with global reach.

Restoring Balance in

Human Biology

Ashta Therapeutics is an emerging biotech restoring balance in human biology through precision immunology - pioneering a first-in-class GPCR mechanism with global reach.

Biology

Biology Works in Balance.

Biology Works in Balance.

Biology Works in Balance.

So Should Medicine.

So Should Medicine.

So Should Medicine.

The human body constantly regulates itself - temperature, immunity, metabolism through a delicate system called homeostasis.
Inflammation is part of this system.
It protects. It heals. But when it doesn’t stop, it harms.
Chronic inflammation sits at the core of many serious diseases.

We don’t just suppress symptoms.

We aim to restore balance at the source.

A Different Way to Think

A Different Way to

A Different Way to Think

About Disease

Think About Disease

About Disease

In Indian philosophy, balance sustains life.
We apply this principle to biology where disease emerges when balance is lost.

Abundance

The biological universe is vast. Millions of proteins, trillions of interactions yet only a fraction explored.

Prosperity

Our pursuit is simple: help people live healthier, longer lives.

Harmony

Every system in the body thrives on balance. When it breaks, disease emerges.

What We’re Building

Precision Biology.

Precision Biology.

Precision Biology.

Designed for Outcomes.

Designed for Outcomes.

Designed for Outcomes.

We are building a new class of therapies grounded in precision immunology - targeting the exact mechanisms that drive disease.

01

Precision Immunology

Deep understanding of immune pathways driving inflammation, with a differentiated view of C3aR across key cytokine systems.

02

Precision Chemistry

Computational chemistry, physics-based AI/ML and structural biology applied to identify and design molecules for complex GPCR targets.

03

Precision Execution

Focused experiments, sharp screening and disciplined decision-making - optimised for speed and capital efficiency.

Our Edge

A Validated Class.

A Validated Class.

A Validated Class.

A Differentiated Mechanism.

A Differentiated Mechanism.

A Differentiated Mechanism.

We focus on GPCR biology - one of the most successful classes of drug targets - with significant untapped potential.

One mechanism. Broad therapeutic potential.

One Mechanism.

One Mechanism.

One Mechanism.

Multiple Disease Opportunities.

Multiple Disease Opportunities.

Our pipeline is focused on immune-driven diseases with high unmet need, leveraging a key mechanism with broad biological reach.

Program

HITS

INITIAL POC.

SAFETY

PK/PD

glp

Phase 1

Asthma

Nebuliser / Dry Powder

SAFETY

COPD

Nebuliser / Dry Powder

SAFETY

CRSwNP

Oral / Nasal Spray

HITS

Kidney

Oral

HITS

Others

Oral

HITS

Team

Experience Across the Full

Experience Across the Full

Experience Across the Full

Drug Discovery Lifecycle

Drug Discovery Lifecycle

Drug Discovery Lifecycle

Our founding team brings decades of experience across discovery, development, strategy and commercialisation.

Dr Abishek Iyer

18+ years in drug discovery spanning academia and industry. Established discovery lab and led cross-functional teams at Alembic Pharma. Experience in GPCR targets including GLP-1R, PAR2, C5aR and C3aR.

Mr Jesal Shah

30+ years across pharmaceuticals and investments. Led US generic and innovation strategy for 10 years managing teams across Medical, Peptides, Discovery, IP. Identified & executed cross-border in-licensing and strategic investment transactions in innovation.

Dr MS Mohan

40+ years in R&D leadership. Founded Orbicular Pharma for developing complex generic products. Leadership roles across big pharma organisations. Developed and launched oral solids, injectables, inhalation and topical products in regulated markets.

Dr Rahul Gawande

25+ years experience across pharmaceutical manufacturing, operational scale-up and execution within regulated healthcare environments.

Dr Bhavesh Patel

25+ years experience in pharma with expertise in complex formulations, specialty drug delivery systems and pharmaceutical product development.

Medicine Is Entering

Medicine Is Entering

Medicine Is Entering

a More Precise Era

a More Precise Era

a More Precise Era

For decades, many therapies have relied on broadly suppressing disease pathways - often at the cost of precision, durability or tolerability.

We believe the future of medicine will come from targeting the specific biological mechanisms that drive disease at its source. As our understanding of human biology deepens, therapeutics can become more targeted, more scalable, and ultimately more effective for patients.

Silhouette of a researcher examining a slide under a microscope with a blue background.

Build the Future of

Medicine With Us

We partner with researchers, clinicians, companies and investors who share our conviction in precision science and global impact.

Build the
Future of Medicine

With Us

We partner with researchers, clinicians, companies and investors who share our conviction in precision science and global impact.

Build the Future of

Medicine With Us

We partner with researchers, clinicians, companies and investors who share our conviction in precision science and global impact.